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Disease or Condition — Cancer, Tumors, and Abnormal Cell Growth:
AML with t(8;21)(q22;q22)

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Acute myeloid leukemia (AML) is a type of cancer that affects the blood and bone marrow. It is characterized by the rapid growth of abnormal white blood cells, called myeloblasts, which crowd out healthy blood cells. The t(8;21)(q22;q22) chromosomal translocation is a specific genetic abnormality that is found in some cases of AML. This translocation involves the exchange of genetic material between chromosomes 8 and 21, resulting in the fusion of two genes, RUNX1 and CBFB, which are involved in the regulation of cell growth and differentiation. This fusion gene leads to the production of an abnormal protein that causes the uncontrolled growth of myeloblasts.

  • acute myeloid leukemia with t(8;21)(q22;q22)
Basic Lab Tests (measurements)

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