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Description

Type II autoimmune polyendocrine syndrome (APS-II) is an autoimmune disorder characterized by the presence of two or more autoimmune diseases. It is caused by an abnormal immune response that leads to the production of autoantibodies that attack the body's own tissues and organs. Common autoimmune diseases associated with APS-II include Addison's disease, hypoparathyroidism, vitiligo, pernicious anemia, and type 1 diabetes. Symptoms of APS-II can vary depending on the affected organs, but may include fatigue, weight loss, muscle weakness, and skin rashes. Treatment typically involves medications to suppress the immune system and replace hormones or other substances that are deficient.

Synonyms

• APS2
• PGA II
• Schmidt syndrome
• Type II autoimmune polyendocrine syndrome
• Type II polyendocrine autoimmune syndrome
• Type II polyglandular autoimmune syndrome

Detailed Disease and Condition Information (use the search buttons below to find details on these topics)
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