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Disease or Condition — Infections and Parasites:
African sleeping sickness

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African trypanosomiasis, also known as sleeping sickness, is a vector-borne parasitic disease caused by the protozoan Trypanosoma brucei. It is transmitted to humans through the bite of an infected tsetse fly. Symptoms of the disease include fever, headaches, joint pain, and swelling of the lymph nodes. In the later stages, the disease can cause confusion, difficulty sleeping, and even coma. Treatment for African trypanosomiasis includes drugs such as pentamidine and suramin.

  • African trypanosomiasis
  • nagana
  • sleeping sickness
  • T. brucei infection
  • Trypanosoma brucei infection
Symptoms (patient's findings)
  • abnormal weight loss
  • anorexia
  • depression
  • headache
  • joint pain
  • malaise
  • muscle pain
Signs (examiner's findings)
  • convulsions
  • generalized enlarged lymph nodes
  • hepatomegaly
  • macular rash
  • muscle rigidity
  • psychosis
  • sensory abnormality
  • splenomegaly
  • urticaria
Basic Lab Tests (measurements)

Detailed Disease and Condition Information (use the search buttons below to find details on these topics)
All of the following must be considered when interpreting clinical findings and are too extensive to be covered on this site: