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Disease or Condition — Injuries and Poisoning:
Amanita phalloides mushroom toxicity

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Amanita phalloides, commonly known as the death cap mushroom, is a highly toxic mushroom found in many parts of the world. It contains a number of toxins, including amatoxins, which are responsible for its toxicity. Amatoxins are cyclic peptides that inhibit the enzyme RNA polymerase II, which is essential for the production of proteins in the body. This leads to cell death and organ failure, and can be fatal if not treated quickly. Symptoms of Amanita phalloides poisoning include nausea, vomiting, abdominal pain, and diarrhea, followed by liver and kidney failure. Treatment typically involves supportive care and the administration of activated charcoal to absorb the toxins.

  • 'death cap' poisoning
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