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A trial septal defect (ASD) is a hole in the wall (septum) that separates the two upper chambers of the heart (the atria). This hole allows oxygen-rich blood from the left atrium to mix with oxygen-poor blood from the right atrium. This can cause an abnormal increase in blood flow to the lungs, leading to an increased risk of pulmonary hypertension and other complications. An ASD can be congenital (present at birth) or acquired (developing later in life). Treatment for an ASD typically involves closing the hole with a device or surgery.
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