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Beta-2-microglobulin-associated amyloidosis is a rare type of amyloidosis caused by the accumulation of beta-2-microglobulin (B2M) in the body. B2M is a protein that is normally found on the surface of cells and is involved in the immune system. In this type of amyloidosis, B2M accumulates in the body and forms amyloid deposits in various organs and tissues. These deposits can cause organ damage and lead to a variety of symptoms, including fatigue, joint pain, and swelling. Treatment for this condition typically involves medications to reduce inflammation and slow the progression of the disease.
All of the following must be considered when interpreting clinical findings and are too extensive to be covered on this site: