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Description

Drug-induced aplastic anemia is a rare but serious condition in which the bone marrow fails to produce enough new blood cells. It is caused by certain medications, such as antibiotics, anticonvulsants, and chemotherapy drugs, that damage the bone marrow and interfere with its ability to produce new blood cells. Symptoms of drug-induced aplastic anemia include fatigue, shortness of breath, easy bruising, and frequent infections. Treatment typically involves discontinuing the medication that caused the condition and may include blood transfusions, bone marrow transplants, and medications to stimulate the bone marrow to produce new blood cells.

Synonyms

• bone marrow depression
• drug-induced aplastic anemia
• drug-induced red cell aplasia
• myelosuppression
• myelotoxicity

Symptoms (patient's findings)

• asthenia
• dizziness
• fatigue
• shortness of breath

Signs (examiner's findings)

• mid systolic heart murmur
• pallor

Basic Lab Tests (measurements)

• serum
  •      iron
• whole blood
  •      mean corpuscular volume
  •      hemoglobin
  •      macrocytes
  •      reticulocytes
  •      hemoglobin F
  •      granulocytes
  •      lymphocytes
  •      platelets
  •      eosinophils
  •      leukocytes
  •      neutrophils
  •      basophils
  •      monocytes

Detailed Disease and Condition Information (use the search buttons below to find details on these topics)
All of the following must be considered when interpreting clinical findings and are too extensive to be covered on this site: