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Depression is a mental health disorder characterized by persistent feelings of sadness, emptiness, and hopelessness. It can also cause physical symptoms such as fatigue, changes in appetite, and difficulty sleeping. People with depression may also experience difficulty concentrating, low self-esteem, and feelings of guilt or worthlessness. Depression can be caused by a variety of factors, including genetics, brain chemistry, and life events. Treatment for depression typically involves a combination of medication, psychotherapy, and lifestyle changes.
All of the following must be considered when interpreting clinical findings and are too extensive to be covered on this site: