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Disease or Condition — Muscle, Bone, and Connective Tissue Disorders:
drug-induced lupus erythematosus

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Drug-induced lupus erythematosus (DILE) is a type of lupus that is caused by certain medications. It is an autoimmune disorder that is characterized by inflammation of the skin, joints, and other organs. Symptoms of DILE can include joint pain, fatigue, fever, skin rashes, and chest pain. DILE is usually triggered by certain medications, such as hydralazine, procainamide, and quinidine. Treatment for DILE typically involves discontinuing the medication that is causing the symptoms and treating the symptoms with anti-inflammatory medications.

  • DILE
  • drug-induced lupus
Symptoms (patient's findings)
  • abnormal weight loss
  • facial rash
  • fatigue
  • fever
  • joint pain
  • joint swelling
  • muscle pain
  • painless mouth ulcer
Signs (examiner's findings)
  • acute skin ultraviolet photosensitivty
  • hepatomegaly
  • malar rash
  • pharyngeal ulcer
  • pleural effusion
  • splenomegaly
  • ulcerative oral mucositis
Basic Lab Tests (measurements)

Detailed Disease and Condition Information (use the search buttons below to find details on these topics)
All of the following must be considered when interpreting clinical findings and are too extensive to be covered on this site: