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Description

Drug-induced lupus erythematosus (DILE) is a type of lupus that is caused by certain medications. It is an autoimmune disorder that is characterized by inflammation of the skin, joints, and other organs. Symptoms of DILE can include joint pain, fatigue, fever, skin rashes, and chest pain. DILE is usually triggered by certain medications, such as hydralazine, procainamide, and quinidine. Treatment for DILE typically involves discontinuing the medication that is causing the symptoms and treating the symptoms with anti-inflammatory medications.

Synonyms

• DILE
• drug-induced lupus

Symptoms (patient's findings)

• abnormal weight loss
• facial rash
• fatigue
• fever
• joint pain
• joint swelling
• muscle pain
• painless mouth ulcer

Signs (examiner's findings)

• acute skin ultraviolet photosensitivty
• hepatomegaly
• malar rash
• pharyngeal ulcer
• pleural effusion
• splenomegaly
• ulcerative oral mucositis

Basic Lab Tests (measurements)

• body
  •      weight change
  •      weight
• serum
  •      homogeneous antinuclear antibody pattern
  •      rheumatoid factor
  •      nuclear antibody
  •      ss-DNA Ab
  •      speckled antinuclear antibody pattern
  •      cardiolipin Ab
• vital signs
  •      temperature
• whole blood
  •      hemoglobin
  •      lupus erythematosus cells
  •      hematocrit
  •      erythrocyte sedimentation rate
  •      erythrocytes
  •      platelets
  •      leukocytes

Detailed Disease and Condition Information (use the search buttons below to find details on these topics)
All of the following must be considered when interpreting clinical findings and are too extensive to be covered on this site: