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Pralidoxime (also known as 2-PAM) is a medication used to treat poisoning caused by certain types of nerve agents and organophosphate insecticides. It works by restoring the activity of an enzyme called acetylcholinesterase, which is inhibited by nerve agents and organophosphates.

Common side effects of pralidoxime include nausea, vomiting, headache, dizziness, and muscle weakness. Other more serious side effects may include seizures, difficulty breathing, and an irregular heartbeat.

Brand names associated with pralidoxime include Protopam, Protopam Chloride, and Regonol.

  • pralidoxime
  • anticholinergic antidote
  • cholinesterase inhibitor antagonist

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