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Nucleated erythrocytes are immature red blood cells that are present in the peripheral blood of a patient. They are typically acquired from a patient's whole blood sample. The most common method for obtaining nucleated erythrocytes is through a process called differential centrifugation. This involves spinning the whole blood sample in a centrifuge at a high speed, which separates the components of the blood based on their density. The nucleated erythrocytes are then collected from the top layer of the sample. Other methods for obtaining nucleated erythrocytes include manual counting of the cells in a blood smear or using a flow cytometer to count the cells. The clinical test for nucleated erythrocytes is used to diagnose certain conditions, such as anemia, leukemia, and other blood disorders.
All of the following must be considered when interpreting clinical findings and are too extensive to be covered on this site: