Simplifying Science Descipher Logo   
Disease or Condition — Hormonal, Nutritional, Metabolic, and Immune Disorders:
AGL deficiency

Information displayed below is a subset of the entire knowledge base and may be incorrect, or incomplete intensionally or inadvertently. If you detect a serious error or want access to the complete knowledge base, please contact us.


Type III glycogen storage disease, also known as Cori's disease or Forbes disease, is a rare inherited disorder caused by a deficiency of the enzyme glycogen debranching enzyme (GDE). This enzyme is responsible for breaking down glycogen, a form of sugar stored in the body, into glucose, which is used for energy. Without GDE, glycogen accumulates in the liver, muscles, and other tissues, leading to a variety of symptoms. These can include muscle weakness, fatigue, poor growth, and liver and kidney problems. Treatment typically involves dietary changes and medications to help manage symptoms.

  • amylo-1-6-glucosidase deficiency
  • Cori disease
  • debrancher deficiency
  • debranching enzyme deficiency
  • Forbes disease
  • GDE deficiency
  • glycogen debrancher deficiency
  • glycogen debranching enzyme deficiency
  • GSD3
  • limit dextrinosis
  • Type III glycogen storage disease
Basic Lab Tests (measurements)

Detailed Disease and Condition Information (use the search buttons below to find details on these topics)
All of the following must be considered when interpreting clinical findings and are too extensive to be covered on this site: