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Type IV renal tubular acidosis (RTA) is a type of metabolic acidosis caused by a defect in the kidney's ability to reabsorb bicarbonate (HCO3-) from the urine. This results in an inability to maintain normal acid-base balance in the body, leading to an accumulation of acid in the blood. Symptoms of type IV RTA include fatigue, muscle weakness, nausea, vomiting, and dehydration. Treatment typically involves the use of alkali therapy, which helps to neutralize the acid in the blood and restore normal acid-base balance.
All of the following must be considered when interpreting clinical findings and are too extensive to be covered on this site: