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Intrahepatic cholestasis is a condition in which the flow of bile from the liver is blocked or reduced. Bile is a fluid produced by the liver that helps to digest fats and remove waste products from the body. When the flow of bile is blocked or reduced, it can cause a buildup of bile acids in the liver and bloodstream, leading to a variety of symptoms, including jaundice, itching, dark urine, pale stools, and abdominal pain. Treatment for intrahepatic cholestasis may include medications to reduce bile acid levels, dietary changes, and lifestyle modifications. In some cases, a liver transplant may be necessary.
All of the following must be considered when interpreting clinical findings and are too extensive to be covered on this site: