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Primary sclerosing cholangitis (PSC) is a chronic, progressive liver disease characterized by inflammation and scarring of the bile ducts. It is a rare disorder that affects the bile ducts, which are the tubes that carry bile from the liver to the small intestine. Symptoms of PSC can include jaundice, itching, fatigue, abdominal pain, and weight loss. PSC can lead to cirrhosis, liver failure, and even liver cancer. Treatment for PSC includes medications to reduce inflammation, antibiotics to treat infections, and liver transplantation.
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