Simplifying Science Descipher Logo   
S T E M
Disease or Condition — Blood Disorders:
Addison's anemia

Information displayed below is a subset of the entire knowledge base and may be incorrect, or incomplete intensionally or inadvertently. If you detect a serious error or want access to the complete knowledge base, please contact us.

Description

Pernicious anemia is a type of anemia caused by a lack of vitamin B12. It occurs when the body is unable to absorb enough vitamin B12 from the diet. This can lead to a decrease in red blood cells, which can cause symptoms such as fatigue, shortness of breath, pale skin, and a weakened immune system. Pernicious anemia is most commonly caused by an autoimmune disorder, in which the body's immune system mistakenly attacks the cells that produce stomach acid, which is necessary for the absorption of vitamin B12. Treatment typically involves taking vitamin B12 supplements and eating foods that are rich in vitamin B12.

Synonyms
  • Addison-Biermer anemia
  • Biermer's anemia
  • macrocytic achylic anemia
  • pernicious anemia
Symptoms (patient's findings)
  • abdominal pain
  • anorexia
  • asthenia
  • constipation
  • dizziness
  • fatigue
  • flatulence
  • heartburn
  • lack of coordination
  • nausea
  • shortness of breath
  • skin paresthesia
  • tongue pain
  • unsteadiness on feet
  • urinary retention
  • vomiting
Signs (examiner's findings)
  • abdominal rigidity
  • atrophic glossitis
  • dementia
  • hallucination
  • hepatomegaly
  • jaundice
  • low-grade fever
  • mid systolic heart murmur
  • pallor
  • proprioception impairment
  • splenomegaly
Basic Lab Tests (measurements)

Detailed Disease and Condition Information (use the search buttons below to find details on these topics)
All of the following must be considered when interpreting clinical findings and are too extensive to be covered on this site:

S