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Description

Chronic lymphocytic leukemia (CLL) is a type of cancer that affects the white blood cells, specifically the B-cells. It is a slow-growing cancer that can cause the body to produce too many abnormal B-cells. These abnormal B-cells are unable to fight infection and can crowd out healthy white blood cells, red blood cells, and platelets. Symptoms of CLL can include fatigue, swollen lymph nodes, and an enlarged spleen. Treatment for CLL can include chemotherapy, radiation therapy, and targeted therapy.

Synonyms

• chronic lymphocytic leukemia

Symptoms (patient's findings)

• abdominal pain
• anorexia
• bleeding tendency
• bone pain
• chest pain on breathing
• easy bruising
• fatigue
• fever
• painless axillary swelling
• painless inguinal swelling
• painless neck localized skin swelling
• shortness of breath

Signs (examiner's findings)

• generalized enlarged lymph nodes
• history of recurrent infections
• splenomegaly

Basic Lab Tests (measurements)

• body
  •      enlarged lymph nodes
• plasma
  •      lactoferrin
  •      hemoglobin
• serum
  •      aldolase
  •      cold agglutinins
  •      adenosine deaminase
  •      alanine aminotransferase
  •      soluble intercellular adhesion molecule-1
  •      cholesterol
  •      immunoglobulin E
  •      vitamin B12
  •      lactate dehydrogenase isoenzyme-1
  •      magnesium
  •      phospholipase A
  •      albumin
  •      lysozyme
  •      angiotensin-converting enzyme
  •      liver alkaline phosphatase
  •      soluble CD40 ligand
  •      carcinoembryonic antigen
  •      bilirubin
  •      immunoglobulin A
  •      vitamin B12 binding capacity
  •      lactate dehydrogenase
  •      phosphoglycerate mutase
  •      zinc
  •      beta-2-microglobulin
  •      indirect bilirubin
  •      protein
  •      heat-stable alkaline phosphatase
  •      interleukin-6
  •      immunoglobulin M
  •      lactate dehydrogenase isoenzyme-5
  •      sodium
  •      total alkaline phosphatase
  •      soluble transferrin receptor
  •      aspartate aminotransferase
  •      soluble c-kit
  •      calcium
  •      urea nitrogen
  •      immunoglobulin G
  •      lactate dehydrogenase isoenzyme-2
  •      5'-nucleotidase
• urine
  •      creatine
  •      calcium
  •      red urine
  •      pseudouridine
  •      cloudy urine
  •      neopterin
  •      Bence-Jones protein
  •      uric acid
  •      urine color
• vital signs
  •      temperature
• whole blood
  •      hemoglobin
  •      leukocytes
  •      macrocytes
  •      plasma cells
  •      reticulocytes
  •      unidentified blasts
  •      hematocrit
  •      neutrophils
  •      mean corpuscular volume
  •      granulocytes
  •      lymphocytes
  •      smudge cells
  •      atypical lymphocytes
  •      erythrocytes
  •      monocytes
  •      platelets
  •      Pelger Huet cells

Detailed Disease and Condition Information (use the search buttons below to find details on these topics)
All of the following must be considered when interpreting clinical findings and are too extensive to be covered on this site: