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Glucocorticoid-excess adrenal cortical hyperfunction is a condition in which the adrenal glands produce too much of the hormone cortisol. This can lead to a variety of symptoms, including weight gain, fatigue, muscle weakness, high blood pressure, and increased thirst and urination. It can also cause changes in mood, such as anxiety and depression. In some cases, it can lead to Cushing's syndrome, a condition in which the body produces too much cortisol and other hormones. Treatment for glucocorticoid-excess adrenal cortical hyperfunction typically involves medications to reduce cortisol levels and lifestyle changes to reduce stress.
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